The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI to repress long-term potentiation.
Naghdi N, Goodwin N, Pocket S. (1998). 'Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation', Iranian Biomedical Journal, 2(3), pp. 129-131.
CHICAGO
N Naghdi, N Goodwin and S Pocket, "Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation," Iranian Biomedical Journal, 2 3 (1998): 129-131,
VANCOUVER
Naghdi N, Goodwin N, Pocket S. Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation. Iranian Biomedical Journal. 1998;2(3):129-131.
Iranian Biomedical Journal