Elevated amount of the free radicals due to ionizing radiation causes deteriorating damage on immune system. Therefore, we made attempts to investigate the protective effect of vitamin E (vit-E), a biological antioxidant in BALB/c mice, so as to find an affordable prophylactic supplementation for individuals who are at risk. Several groups of mice were selected and exposed to sub-lethal g -irradiation with or without vit-E supplementation. At the end of exposure, mice were immunized by either live attenuated Brucellamelitensis vaccine or sheep red blood cell (SRBC). Consequently, the following parameters were assayed: specific antibody response, delayed type hypersensitivity and lymphocyte proliferation. We showed that vit-E supplementation restored the immune response in g -irradiated mice. These findings might have implications for individuals who are at risk of exposure to ionizing radiation.
K. Ardestani,S , Amani,M and kariminia,A . (2000). Restorative Effect of Vitamin E on some Immunological Parameters of Sub-Lethal γ-Irradiated BALB/c Mice. Iranian Biomedical Journal, 4(1), 51-55.
MLA
K. Ardestani,S , , Amani,M , and kariminia,A . "Restorative Effect of Vitamin E on some Immunological Parameters of Sub-Lethal γ-Irradiated BALB/c Mice", Iranian Biomedical Journal, 4, 1, 2000, 51-55.
HARVARD
K. Ardestani S, Amani M, kariminia A. (2000). 'Restorative Effect of Vitamin E on some Immunological Parameters of Sub-Lethal γ-Irradiated BALB/c Mice', Iranian Biomedical Journal, 4(1), pp. 51-55.
CHICAGO
S K. Ardestani, M Amani and A kariminia, "Restorative Effect of Vitamin E on some Immunological Parameters of Sub-Lethal γ-Irradiated BALB/c Mice," Iranian Biomedical Journal, 4 1 (2000): 51-55,
VANCOUVER
K. Ardestani S, Amani M, kariminia A. Restorative Effect of Vitamin E on some Immunological Parameters of Sub-Lethal γ-Irradiated BALB/c Mice. Iranian Biomedical Journal. 2000;4(1):51-55.
Iranian Biomedical Journal