Phenylketonuria (PKU) is one of the most common metabolic inborn diseases caused by mutations in the phenylalanine hydroxylase (PAH) gene. This gene is linked to a variable number of tandem repeats (VNTR) region which is a polymorphic marker that facilitates the implementation of prenatal diagnosis and carrier screening. In this study, VNTR with 13 repeats that has not been reported previously was observed in 2 PKU families from Fars province, south of Iran. This allele showed 4% frequency in normal individuals
Kamkar,M , Saadat,M , Saadat,I and Haghighi,G . (2003). Report of VNTR with 13 Repeats Linked to Phenylalanine Hydroxylase Locus in Unaffected Members of Two PKU Families. Iranian Biomedical Journal, 7(2), 89-90.
MLA
Kamkar,M , , Saadat,M , , Saadat,I , and Haghighi,G . "Report of VNTR with 13 Repeats Linked to Phenylalanine Hydroxylase Locus in Unaffected Members of Two PKU Families", Iranian Biomedical Journal, 7, 2, 2003, 89-90.
HARVARD
Kamkar M, Saadat M, Saadat I, Haghighi G. (2003). 'Report of VNTR with 13 Repeats Linked to Phenylalanine Hydroxylase Locus in Unaffected Members of Two PKU Families', Iranian Biomedical Journal, 7(2), pp. 89-90.
CHICAGO
M Kamkar, M Saadat, I Saadat and G Haghighi, "Report of VNTR with 13 Repeats Linked to Phenylalanine Hydroxylase Locus in Unaffected Members of Two PKU Families," Iranian Biomedical Journal, 7 2 (2003): 89-90,
VANCOUVER
Kamkar M, Saadat M, Saadat I, Haghighi G. Report of VNTR with 13 Repeats Linked to Phenylalanine Hydroxylase Locus in Unaffected Members of Two PKU Families. Iranian Biomedical Journal. 2003;7(2):89-90.
Iranian Biomedical Journal